Glossary of Abbreviations:BMI (Body mass index), BSA (body surface area), CI (confidence interval), CTA (computed tomography angiography), ECC (extracorporeal circulation), FET (Frozen elephant trunk), FFP (fresh frozen plasma), GFR (glomerular filtration rate), HCA (hypothermic circulatory arrest), HIT (heparin induced thrombopenia), ICU (intensive care unit), ILT (intraluminal thrombus), INR (international normalized ratio), IQR (interquartile range), MRI (magnetic resonance imaging), OR (Odds ratio), PBC (packed blood cells), PC (platelet concentrate), POD (postoperative day), PTT (partial thromboplastin time), SACP (selective antegrade cerebral perfusion), VSARR (valve sparing aortic root replacement)
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to The Journal of Thoracic and Cardiovascular Surgery
Publication stageIn Press Journal Pre-Proof
Sources of Funding: none.
Conflicts of interest: Shrestha M. and Haverich A. declare that they served as consultants for Terumo Aortic during the study period. All other authors declare that they have no conflicts of interest.
Institutional Review Board Approval: IRB #1698-2013 (January 25th, 2013); IRB #10162_BO_K_2022 (January 14th, 2022). Informed consent was obtained.
Frozen elephant trunk implantation may lead to intraluminal thrombosis within the stent graft. Therapeutic anticoagulation should be considered in patients at risk. Early imaging should be performed.
We believe that the incidence of ILT after FET implantation is underreported in our study. Further research should focus on early postoperative imaging and risk stratification. Stent graft designs should be improved to reduce surface thrombogenicity and slow flow areas within the stent grafts.
Central Picture Legend: Intraluminal thrombosis within a frozen elephant trunk graft on postoperative day 8.