Abbreviations and Acronyms:ASO (arterial switch operation), BAS (balloon atrial septostomy), CPB (cardiopulmonary bypass), TGA/IVS (d-loop transposition of the great arteries with intact intraventricular septum), ECLS (extracorporeal life support), LOS (length of stay), LCOS (low cardiac output syndrome), PICU (paediatric intensive care unit), PGE1 (prostaglandin E1), PPHN (persistent pulmonary hypertension of the newborn), ECMO (extracorporeal membrane oxygenation), VIS (vasoactive-inotropic score)
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to The Journal of Thoracic and Cardiovascular Surgery
Publication stageIn Press Journal Pre-Proof
Conflict of interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
IRB: The study protocol was approved by the Auckland District Health Board research review committee with a waiver of consent (Approval Number: A+8017; approval date: 3rd April 2018)
Central Picture: Emergency ASO rather than preoperative ECLS for TGA/IVS and life-threatening hypoxaemia
Central Message: An emergency ASO provides acceptable outcomes for infants with TGA/IVS and life-threatening refractory hypoxaemia likely due to coexistent pulmonary hypertension.
Perspective: This is the largest case series describing the outcomes of an emergency ASO as treatment for TGA/IVS and severe intractable hypoxaemia. Although mortality is higher compared to those who received a non-emergency ASO, the 30-day mortality and neurodevelopmental outcome is acceptable. Use of an emergency ASO may avoid the risks associated with preoperative ECLS and thus encourage a change in practice.