Abbreviations and acronyms:INR (International normalized ratio), MELD (model for end-stage liver disease), MELD-Na (model for end-stage liver disease with sodium), RV S’ (right ventricular systolic excursion velocity), TAPSE (tricuspid anular plane systolic excursion), TR (tricuspid regurgitation)
Publication stageIn Press Journal Pre-Proof
Funding: This study was funded in part by the Drs. Sidney and Becca Fleischer Heart and Vascular Education Chair, the Peter and Elizabeth C. Tower and Family Endowed Chair in Cardiothoracic Research, James and Sharon Kennedy, the Slosburg Family Charitable Trust, Stephen and Saundra Spencer, and Martin Nielsen.
Disclosures: No author has a relationship with industry or other entity to report.
IRB: #4826; approval renewed through December 2021, with patient consent waived
This study supports expanding the criteria for isolated tricuspid valve surgery in patients with right heart failure, and earlier surgery for functional severe tricuspid regurgitation.
Survival after isolated tricuspid valve surgery for structural & functional regurgitation. 68% CI
Patients with right heart failure undergoing isolated tricuspid valve surgery have either structural or functional tricuspid regurgitation (TR) with similar right ventricular function, but those with functional TR have worse right heart failure. Good early outcomes suggest expanding selection criteria for surgery, and worse survival suggests earlier surgery for patients with functional TR.