Abbreviations and Acronyms:ACEI (angiotensin-converting enzyme inhibitor), ARB (angiotensin receptor blocker), CABG (coronary artery bypass grafting), CAD (coronary artery disease), CV (cardiovascular), HF (heart failure), KCCQ (Kansas City Cardiomyopathy Questionnaire), LV (left ventricular), LVEF (left ventricular ejection fraction), MI (myocardial infarction), NYHA (New York Heart Association), OMT (optimal medical therapy), PCI (percutaneous coronary intervention), STICH (Surgical Treatment for Ischemic Heart Failure)
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to The Journal of Thoracic and Cardiovascular Surgery
- 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines.Circulation. 2013; 128: e240-e327
- Inadequate reporting of concomitant drug treatment in cardiovascular interventional head-to-head trials.Clin Cardiol. 2012; 35: 255-256
- Compliance with guideline-directed medical therapy in contemporary coronary revascularization trials.J Am Coll Cardiol. 2018; 71: 591-602
- Use of medications for secondary prevention after coronary bypass surgery compared with percutaneous coronary intervention.J Am Coll Cardiol. 2013; 61: 295-301
- Medication nonadherence: a diagnosable and treatable medical condition.JAMA. 2013; 309: 2105-2106
- Long-term adherence to evidence-based secondary prevention therapies in coronary artery disease.Circulation. 2006; 113: 203-212
- Preventing recurrent events long term after coronary artery bypass graft: suboptimal use of medications in a population study.Am Heart J. 2004; 147: 1047-1053
- Patterns and predictors of statin use after coronary artery bypass graft surgery.J Thorac Cardiovasc Surg. 2007; 134: 932-938
- Cardiac medical therapy in patients after undergoing coronary artery bypass graft surgery: a review of randomized controlled trials.J Am Coll Cardiol. 2005; 45: 177-184
- Coronary-artery bypass surgery in patients with ischemic cardiomyopathy.N Engl J Med. 2016; 374: 1511-1520
- The rationale and design of the surgical treatment for ischemic heart failure (STICH) trial.J Thorac Cardiovasc Surg. 2007; 134: 1540-1547
- Coronary-artery bypass surgery in patients with left ventricular dysfunction.N Engl J Med. 2011; 364: 1607-1616
- A randomized trial of coronary artery bypass surgery. Survival of patients with a low ejection fraction.N Engl J Med. 1985; 312: 1665-1671
- Mortality and morbidity reduction with Candesartan in patients with chronic heart failure and left ventricular systolic dysfunction: results of the CHARM low-left ventricular ejection fraction trials.Circulation. 2004; 110: 2618-2626
- Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease.N Engl J Med. 2009; 360: 961-972
- Adherence to secondary prevention medications and four-year outcomes in outpatients with atherosclerosis.Am J Med. 2013; 126: 693-700.e1
- Optimal medical therapy improves clinical outcomes in patients undergoing revascularization with percutaneous coronary intervention or coronary artery bypass grafting: insights from the synergy between percutaneous coronary intervention with TAXUS and cardiac surgery (SYNTAX) trial at the 5-year follow-up.Circulation. 2015; 131: 1269-1277
- Coronary artery bypass graft versus percutaneous coronary intervention: meds matter: impact of adherence to medical therapy on comparative outcomes.Circulation. 2016; 134: 1238-1246
- Medical treatment and revascularization options in patients with type 2 diabetes and coronary disease.J Am Coll Cardiol. 2016; 68: 985-995
- Medical therapy for heart failure with reduced ejection fraction: the CHAMP-HF registry.J Am Coll Cardiol. 2018; 72: 351-366
- Medication initiation burden required to comply with heart failure guideline recommendations and hospital quality measures.Circulation. 2015; 132: 1347-1353
- Medication adherence: its importance in cardiovascular outcomes.Circulation. 2009; 119: 3028-3035
This work was supported by Grants U01HL69015, U01HL69013, and RO1HL105853 from the National Institutes of Health and National Heart, Lung, and Blood Institute. This work is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung, and Blood Institute or National Institutes of Health.
There is no additional Institutional Review Board approval required for this analysis because this is a post hoc analysis based on the existing STICH database, that is, no new data are collected and consent had been obtained from every patient in the STICH trial.
Clinical Trial Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT00023595.
Working Group: Rafal Dabrowski, MD, PhD,h Ljubomir Djokovic, MD,i Mark Drazner, MD,j Haissam Haddad, MD,k Imtiaz S. Ali, MD,l Matyas Keltai, MD,m Ajay Naik, MD,n George Sopko, MD,o Krzysztof Golba, MD,p Bert Andersson, MD,q Peter Carson, MD,r and Tomasz Kukulski, MDs